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预防医学  2023, Vol. 35 Issue (10): 907-910    DOI: 10.19485/j.cnki.issn2096-5087.2023.10.017
  妇幼保健 本期目录 | 过刊浏览 | 高级检索 |
气管支气管结核患儿并发肺不张的影响因素分析
吴伟丽1, 丁军2, 张晓强2
1.杭州市临平区妇幼保健院儿科,浙江 杭州 311100;
2.浙江大学医学院附属第二医院临平院区,浙江 杭州 311100
Factors affecting the complication of pulmonary atelectasis in children with tracheobronchial tuberculosis
WU Weili1, DING Jun2, ZHANG Xiaoqiang2
1. Department of Pediatrics, Linping District Maternal and Child Health Hospital, Hangzhou, Zhejiang 311100, China;
2. Linping Division, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 311100, China
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摘要 目的 分析气管支气管结核(TBTB)患儿并发肺不张的影响因素,为防治TBTB并发肺不张提供参考。方法 于2018年10月—2023年3月选择浙江大学医学院附属第二医院临平院区儿科收治的TBTB患儿为研究对象,采用自行设计的调查表收集患儿的基本资料、病原学检查和实验室检测结果,采用多因素logistic回归模型分析TBTB患儿并发肺不张的影响因素。结果 纳入TBTB患儿120例,年龄为6个月~12岁,其中<1岁33例,占27.50%;女童71例,占59.17%。并发肺不张患儿25例,占20.83%。多因素logistic回归分析显示,年龄<1岁(OR=1.720,95%CI:1.126~3.358)、TBTB Ⅵ型(OR=1.669,95%CI:1.101~2.236)、C反应蛋白水平高(OR=1.887,95%CI:1.088~2.686)和降钙素原水平高(OR=1.844,95%CI:1.034~2.654)是TBTB患儿并发肺不张的危险因素。结论 年龄<1岁、TBTB Ⅵ型、C反应蛋白水平高和降钙素原水平高可增加TBTB患儿并发肺不张的风险。
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吴伟丽
丁军
张晓强
关键词 气管支气管结核肺不张儿童影响因素    
AbstractObjective To analyze the factors affecting the complication of pulmonary atelectasis among children with tracheobronchial tuberculosis (TBTB), so as to provide the reference for the prevention and treatment of pulmonary atelectasis complicated by TBTB. Methods Children with TBTB admitted to Department of Paediatrics, Linping Division of the Second Affiliated Hospital of Zhejiang University School of Medicine were selected as the study subjects from October 2018 to March 2023. Subjects's basic information, etiological examination results and laboratory testing results were collected using a self-designed questionnaire, and factors affecting the complication of pulmonary atelectasis among children with TBTB were identified using a multivariable logistic regression model. Results A total of 120 children with TBTB were included, with the age of 6 months to 12 years. There were 33 children at ages of less than one year (27.50%), 71 girls (59.17%) and 25 children with TBTB and pulmonary atelectasis (20.83%). Multivariable logistic regression analysis identified less than one year of age (OR=1.720, 95%CI: 1.126-3.358), type Ⅵ of TBTB (OR=1.669, 95%CI: 1.101-2.236), high level of C-reactive protein (OR=1.887, 95%CI: 1.088-2.686) and high level of procalcitonin (OR=1.844, 95%CI: 1.034-2.654) as risk factors for the complication of pulmonary atelectasis in children with TBTB. Conclusion Less than one year of age, type Ⅵ of TBTB, high level of C-reactive protein and high level of procalcitonin may increase the risk of pulmonary atelectasis in children with TBTB.
Key wordstracheobronchial tuberculosis    pulmonary atelectasis    children    influencing factor
收稿日期: 2023-04-13      修回日期: 2023-07-16      出版日期: 2023-10-10
中图分类号:  R521  
基金资助:2023年杭州市医药卫生科技计划项目(B20232013)
作者简介: 吴伟丽,本科,主管护师,主要从事儿科、新生儿科感染性与传染性疾病工作
引用本文:   
吴伟丽, 丁军, 张晓强. 气管支气管结核患儿并发肺不张的影响因素分析[J]. 预防医学, 2023, 35(10): 907-910.
WU Weili, DING Jun, ZHANG Xiaoqiang. Factors affecting the complication of pulmonary atelectasis in children with tracheobronchial tuberculosis. Preventive Medicine, 2023, 35(10): 907-910.
链接本文:  
https://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2023.10.017      或      https://www.zjyfyxzz.com/CN/Y2023/V35/I10/907
[1] LI F Q,TIAN S,HUANG H D,et al.Post-tuberculosis tracheobronchial stenosis:long-term follow-up after self-expandable metallic stents placement and development of a prediction score-the restenosis score[J].Eur J Med Res,2022,27(1):1-12.
[2] HU T T,LI Y S,WANG X H,et al.Early and regular bronchoscopy examination on effect of diagnosis and prognosis for patients with tracheobronchial tuberculosis[J/OL].Front Med(Lausanne),2022,9[2023-07-16].https://doi.org/10.3389/fmed.2022.825736.
[3] YUEN C M,SZKWARKO D,DUBOIS M M,et al.Tuberculosis care models for children and adolescents:a scoping review[J].Bull World Health Organ,2022,100(12):777-788.
[4] VONASEK B J,RABIE H,HESSELING A C,et al.Tuberculosis in children living with HIV:ongoing progress and challenges[J].J Pediatric Infect Dis Soc,2022,11(Suppl.3):72-78.
[5] 宾松涛,胡晓琴,杨炳艳,等.儿童气管支气管结核九例临床特征及误诊分析[J].临床误诊误治,2021,34(4):19-23.
[6] 刘冉,许磊.纤维支气管镜早期介入治疗儿童重症肺炎支原体肺炎合并肺不张的临床疗效[J].中国内镜杂志,2022,28(11):71-76.
[7] 中华医学会结核病学分会,《中华结核和呼吸杂志》编辑委员会.气管支气管结核诊断和治疗指南(试行)[J].中华结核和呼吸杂志,2012,35(8):581-587.
[8] 《中华结核和呼吸杂志》编辑委员会.支气管结核的几点专家共识[J].中华结核和呼吸杂志,2009,32(8):568-571.
[9] 江载芳,申昆玲,沈颖.褚福堂实用儿科学:第8版[M].北京:人民卫生出版社,2012:1290-1292.
[10] SEDDON J A,JOHNSON S,PALMER M,et al.Multidrug-resistant tuberculosis in children and adolescents:current strategies for prevention and treatment[J].Expert Rev Respir Med,2021,15(2):221-237.
[11] BROOKS M B,DUBOIS M M,MALIK A A,et al.Age-specific effectiveness of a tuberculosis screening intervention in children[J].PLoS One,2022,17(2):1-12.
[12] 刘芳,申晨,孙琳,等.儿童气管支气管结核临床和支气管镜下的表现特征[J].中国防痨杂志,2018,40(9):917-923.
[13] 刘芳,焦安夏.儿童气管支气管结核诊疗现状[J].中华实用儿科临床杂志,2020,35(10):743-748.
[14] 刘芳,饶小春,马渝燕,等.252例儿童气管支气管结核分型探讨[J].中华结核和呼吸杂志,2022,45(3):282-288.
[15] 李金沛,曾旋,徐宇翔,等.77例儿童支气管结核气管镜下病变的特点[J].临床肺科杂志,2022,27(10):1548-1550,1554.
[16] 陈晴,吴桂辉,黄涛,等.气管支气管结核患儿并发肺不张的临床特征及危险因素研究[J].中国全科医学,2022,25(8):930-936.
[17] LEBOUENY M,MALOUPAZOA SIAWAYA A C,BOUANGA L D J,et al.Changes of c-reactive protein and procalcitonin after four weeks of treatment in patients with pulmonary TB[J/OL].J Clin Tuberc Other Mycobact Dis,2023,31[2023-07-16].https://doi.org/10.1016/j.jctube.2023.100348.
[18] QU S Y,ZHANG Y,WU S,et al.Combined analysis of C-reactive protein in pleural fluid and serum is effective in the differential diagnosis of exudative pleural effusions[J].Ann Transl Med,2021,9(14):1-9.
[19] KANG Y J,PARK H,PARK S B,et al.High procalcitonin,C-reactive protein,and α-1 acid glycoprotein levels in whole blood samples could help rapid discrimination of active tuberculosis from latent tuberculosis infection and healthy individuals[J/OL].Microorganisms,2022,10(10)[2023-07-16].https://doi.org/10.3390/microorganisms10101928.
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